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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A patient presents at a physician's office with gait unsteadiness and clumsiness. The patient has a history of type 2 diabetes mellitus, hypertension, and chronic numbness and tingling of the feet and fingertips.
Examination reveals mild distal wasting, glove-and-stocking sensory impairment, absent ankle jerks, brisk knee jerks, and bilateral Babinski reflexes. Gait is slightly ataxic.
CBC reveals a hemoglobin of 10.1 g/dL, WBC of 4,500 cells/mL, MCV 120 fL, and platelets
163,000 cells/ul.
Which of the following is the most important laboratory test for assisting in diagnosis?

A) Ferritin
B) Serum vitamin B12
C) Folic acid
D) Erythrocyte sedimentation rate

2. A 35-year-old Woman is diagnosed with pustular psoriasis, which covers 35% of her body. She has tried high-potency topical steroid creams and topical coal tar with ultraviolet B treatments in the past, with no effect. Which of the following is the best therapeutic option for this patient?

A) Methotrexate
B) Calcipotriene
C) Halobetasol
D) Anthralin

3. A pharmacy resident calculates the appropriate gentamicin dose and frequency for an elderly patient on hemodialysis. This skill reflects what type of residency learning?

A) Application
B) Comprehension
C) Analysis
D) Evaluation

4. Administration of a marketed drug to a patient for an off-label indication without approval from a local IRB is permissible in which of the following situations?

A) The drug is administered under a protocol sponsored by an NIH grant.
B) The patient's physician has filed a Notice of Claimed Investigational Exemption for a New Drug with the FDA.
C) The patient's physician considers that the risk/benefit ratio favors the use of the drug.
D) The drug is administered on the request of the patient or the patient's representative.

5. Which is the most effective method to improve the safety of the use of phytonadione in an institution with a 24-hour pharmacy?

A) Establishment of emergency preparedness kits containing phytonadione to be stored in the patient care areas where warfarin is used
B) Computer order sets that default to using a standardized number of vials or amps of phytonadione per dose
C) Removal of phytonadione from all patient care areas of the facility coupled with strict usage guidelines
D) Yearly in-service education and medical staff presentation about phytonadione use

Solutions: